maandag 7 mei 2012

Free Auto Blogger Report

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Pagetoid reticulosis in a prepubescent boy successfully treated with photodynamic therapy

Pagetoid reticulosis or Woringer–Kolopp disease (WKD) is a rare variant of mycosis fungoides, consisting of localized patches or plaques containing intraepidermal proliferations of neoplastic T cells in a pagetoid distribution (similar to that of the adenocarcinomatous cells found in Paget disease of the nipple), which typically affects middle-aged and elderly men. We report a trial of photodynamic therapy (PDT) with topical aminolaevulinic acid (ALA), carried out on a 10-year-old boy with a solitary lesion of WKD on his foot, to avoid the long-term problems associated with the typical treatments for WKD of surgery and/or local irradiation. The plaque progressively flattened during treatment, and after nine PDT sessions over 13 months, the patient was clinically free of disease. PDT may be a viable alternative to surgery and local irradiation for localized cutaneous T-cell lymphoma, including WKD, especially in younger patients.
Read More... [Source: Clinical and Experimental Dermatology - Posted by FreeAutoBlogger]

Orofacial granulomatosis: three case reports illustrating the spectrum of disease and overlap with Crohn's disease

We report three cases of orofacial granulomatosis (OFG) to illustrate the spectrum of this disease, and to discuss the appropriate management steps, consider its overlap with Crohn's disease (CD) and raise its awareness among paediatric dermatologists. The term ‘orofacial granulomatosis’ was first used in 1985 to describe granulomas in the orofacial region in the absence of any recognized systemic condition. It is uncommon but becoming increasingly recognized in children. The clinical features of the disease may vary greatly, and often present with subtle changes that can be missed. There is a debate about whether OFG exists as a separate condition or whether it is an oral feature of CD, as some patients go on to develop CD several years later. Identifying those most at risk is important, as ongoing investigations may be necessary. The three cases presented in this series illustrate the range of disease signs and symptoms, and the investigations required.
Read More... [Source: Clinical and Experimental Dermatology - Posted by FreeAutoBlogger]

Free Auto Blogger Report

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Peptidoglycan from Staphylococcus aureus induces T(H)2 immune response in mice.

CONCLUSION: These results suggest that PEG may have the ability to induce the development of T(H)2 cells through insufficient production of IL-12 p70 and excessive production by LCs of homodimeric IL-12 p40, a known antagonist of bioactive IL-12 p70, offering a possible explanation for the role of S aureus colonization in patients with atopic dermatitis. PMID: 22533229 [PubMed - in process] (Source: Journal of Investigational Allergology and Clinical Immunology)
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Indocyanine green fluorescence endoscopy for visual differentiation of pituitary tumor from surrounding structures.

Conclusions Indocyanine green fluorescence endoscopy shows promise as an intraoperative modality to visually distinguish pituitary tumors from normal tissue and to visually identify areas of dural invasion, thereby facilitating complete tumor resection and minimizing injury to surrounding structures. These results support the continued development of fluorescence endoscopic resection techniques. PMID: 22360574 [PubMed - in process] (Source: Journal of Neurosurgery)
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A guide to cable selection for efficient IT networks

Computer Network Cables play a significant role in smooth and effective flow of data across the networks. It is these high quality network cables that transfer audio, video and text files from one network to another within a fraction of a second. These high end network cables are basically audio video cables that are exclusively [...]
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